Symptoms of Pyridoxine (Vitamin B6) Toxicity

Vitamin B6 toicity symptomsVitamin B6, also named pyridoxine, is one of eight water-soluble B vitamins. Vitamin B6 supports more vital bodily functions than any other vitamin. Pantothenic acid is sometimes called the “anti-stress” vitamin.

Vitamin B6 is a coenzyme for several enzyme systems. Pyridoxine is required for the balancing of hormonal changes in women as well as assisting the immune system and the growth of new cells.

Vitamin B6 is not toxic when supplied by food in the diet.
Pantothenic acid supplements usually contain calcium pantothenate in tablets or capsules. Just as there’s no RDA for pantothenic acid, there’s no real overdose level.

Supplemental forms are usually in the form of pyridoxine hydrochloride. The upper limit for adults set by the Institute of Medicine is 100 mg; 100 mg per day is certainly a safe limit, well below the level that might bring on neurological problems.

Supplementation should be controlled as extreme dosage, such as in excess of 2,000 mg per day, may cause neurological damage.

Potential Pyridoxine toxicity symptoms

People on medication for Parkinson’s disease should be careful about taking Vitamin B6 as it can inactivate levodopa.
People taking pyridoxine late at night sometimes experience very vivid dreams.

Vitamin B6 can cause neurological disorders, such as loss of sensation in legs and imbalance, when taken in high doses (200 mg or more per day) over a long period of time.

Pyridoxine toxicity can damage sensory nerves, leading to numbness in the hands and feet as well as difficulty walking.

Symptoms of a pyridoxine overdose may include poor coordination, staggering, numbness, decreased sensation to touch, temperature, and vibration; and tiredness.

Some pantothenic acid is found in almost every food. Good sources are organ meats, salmon, eggs, beans, milk, and whole grains.

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